By Shamlal Mangray, Ronald A. DeLellis (auth.), Michael A. Blake, Giles Boland (eds.)

Imaging of the adrenal gland has made super growth within the final decade as new applied sciences proceed to conform. Adrenal Imaging highlights the pertinent medical and pathological details that underpins the actual interpretation and use of adrenal imaging. Written via a prestigious crew of overseas individuals, person chapters in Adrenal Imaging function a proper and up to date reference of adrenal imaging findings, algorithms and methods in CT, MR nuclear medication, intervention, and trauma. precis sections on the finish of every bankruptcy remove darkness from key educating issues to reinforce retention.

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50 Hyperaldosteronism with High Plasma Renin Activity Bartter’s Syndrome .................................................... Gitelman’s Syndrome ................................................ 50 50 50 Primary Adrenal Insufficiency .................................... Etiology ..................................................................... Clinical Features ........................................................ Diagnosis ...................................................................

Synovial sarcoma), but a spindle cell morphology usually aids in making the distinction. Thyroid transcription factor 1 (TTF-1) is commonly positive in metastatic lung and thyroid carcinomas, but negative in primaries of breast, gastrointestinal tract, liver and kidney. Thyroglobulin (THY) is used to differentiate lung (THY negative) from thyroid carcinoma (THY positive). Other commonly used antibodies include gross cystic disease fluid 15 (GCDFP-15) for breast; CDX2 (protein product of a homeobox gene involved in intestinal development) for gastrointestinal primaries; polyclonal carcinoembryonic antigen (pCEA) and HepPar-1 (a protein of unknown function in liver cells) for hepatocellular carcinoma (HCC); and CD10 (a zinc metallopeptidase expressed in early lymphoid progenitors and normal germinal center cells of lymph nodes) and renal cell carcinoma antigen (RCC), both of which may be expressed in renal cell carcinoma.

These disorders are usually treated by replacement of the deficient steroid hormone and surgical correction of ambiguous genitalia. Adrenal cortical adenomas and carcinomas may develop, though rarely, in the setting of congenital adrenal hyperplasia [12, 92]. Testicular tumors can also arise in affected patients. These lesions are not autonomous neoplasms, since they are dependent on the presence of elevated levels of ACTH. They are commonly bilateral and are most typically located in the hilar regions of the testes.

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