By J. F. Goodwin (auth.), G. Baroldi M.D., F. Camerini M.D., J. F. Goodwin M.D. (eds.)

This publication offers a contemporary survey at the pathophysiological and medical implications of the main widespread sorts of automobile- diomyopathies, together with diagnostic instruments and new pharmaco- logical therapeutical ways. an attractive extra point is the hot information on immunology on dilated cardiomyo- mypathies and surprising dying in youngsters in addition to center transplantation as ultimum cause of remedy.

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Circulation 53:9 15. McKenna WJ, Franklin RCG, Annopoulos PN, Robinson KC, Deanfield JE, Dichie S, Krikler SJ (1988) Arrhythmia and prognosis in infants, children and adolescents with hypertrophic cardiomyopathy. J Am Coli Cardiol 11 (1): 147-153 16. Lewis JF, Maron BJ (1989) Elderly patients with hypertrophic cardiomyopathy: a subset with distinctive left ventricular morphology and progressive clinical course late in life. J Am Coli Cardiol 13 (I): 36-45 17. Louie EK, Maron BJ (1986) Hypertrophic cardiomyopathy with extreme increase in left ventricular wall thickness: functional and morphologic features and clinical significance.

Although no systematic screening of the family members was performed, 27% of the patients had a family history of HCM, 13% of sudden death and 9% had both. Cardiac catheterization was performed in 23% of the cases, and in about one third of them a basal left ventricular outflow tract gradient greater than 30 mmHg was present. 28 F. Cecchi et al. Fourty percent of the patients had at least one run of VT at repeated ambulatory Holter monitoring, which was performed in 141 patients for a mean period of 72 h (range 24-382 h).

Maron Bl, Wolfson lK, Epstein SE, Roberts WC (1986) Intramural ("small vessel") coronary artery disease in hypertrophic cardiomyopathy. 1 Am Coll Cardiol 8:545-557 35. Fiddler GI, Tajik AI, Weidman WH, McGoon DC, Ritter DG, Giuliani ER (1978) Idiopathic hypertrophic subaortic stenosis in the young. Am 1 Cardiol 42:793-799 36. McKena WI, Franklin RCG, Nihoyannopoulos P, Robinson KC, Deanfield JE (1988) Arrhythmia and prognosis in infants, children and adolescents with hypertrophic cardiomyopathy.

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